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secobarbital will decrease the extent or effect of diazepam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Robust or average CYP3A4 inducers might maximize amount of diazepam elimination; as a result, efficacy of diazepam might be diminished.The typical everyday dose to the barbiturate addict is nor